Public Title A Signature Peptide Approach to Proteomics With Isotope Ratio Quantification Division Lead Inventor Regnier, Fred Public Description Protein analyzing is of major importance in the field of genetic research. When analyzing complex proteins the typical strategy is to cleve the proteins with an enzyme and then search the DNA database for fragments that match the mass of the signature peptide. Too often the complex mixtures contain thousands of proteins that may have a hundred thousand or more signature peptides. This causes the process to be extremely lengthy. A new method has been developed for this process. This method is as sensitive to changes in very dilute samples as it is with those that are present with great abundance. This approach also creates an internal standard that makes it esier to measure the changes at these low levels. By targeting the specific signature peptides it is possible to reduce the amount of time necessary for identification. Patent Status Public References Key Words Manager Shane Fimbel Email smfimbel@prf.org Telephone 765-588-3491 Fax 795-463-3486   Back to List