Public Title Pseudotyping Retroviral Vectors With the Marburg Virus Envelope Glycoprotein to Target to Multiple Tissues for Therapeutic Applications Division Lead Inventor Sanders, David Public Description By changing the ligand on a virus (pseudotyping), it is possible to redirect a therapeutic vector to transduce different cell types. Purdue researchers have pseudotyped viral vectors using the envelope glycoproteins from Marburg Virus. The newly created recombinant viruses possess improved cell targeting and/or transduction efficiency and overcome limitations of retroviruses pseudotyped with other commonly used envelope glycoproteins. Patent Status Public References Key Words Biotechnology, Biotechnology/Gene & cell therapy Manager Shane Fimbel Email smfimbel@prf.org Telephone 765-588-3491 Fax 795-463-3486   Back to List